Most commonly skullcap is given for nervousness, either post illness or due to mental or physical exhaustion. Not surprisingly, it is also frequently taken for insomnia due to mental over-activity (picture the restless type who is over-worked and cannot “shut off” at night). Indeed, one of the few double-blind, placebo-controlled studies available on Skullcap showed that the herb did have a “noteworthy” anxiolytic effect on healthy volunteers